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Siemens expands the AI-powered Siemens Xcelerator Portfolio with end-to-end digital threads to connect data from research to life science production.
July 1, 2025 – Siemens AG announced it has completed its acquisition of Dotmatics, a leading provider of Life Sciences R&D software, headquartered in Boston and headquartered in the portfolio of Global Software Investor Insight Partners. Once the transaction is now complete, Dotmatics will form part of Siemens’ Digital Industries Software Business, and will see Siemens’s industry-leading product lifecycle management (PLM) portfolio grow rapidly and expand significantly into the complementary life sciences market.
The acquisition of Dotmatics will strengthen Siemens’ position as a global leader in AI-powered PLM software, allowing Siemens to scale this technology to life sciences and fully address the growth opportunities in this market. Dotmatics’ Scientific Intelligence Platform, Luma, and its industry-leading scientific applications allow AI-powered multimodal drag development, seamless collaboration, and contextualized data to create digital threads connected throughout the research and production value chain.
“We are using Dotmatics to build a new era of innovation in life science. From research to production, we create unique end-to-digital threads. We combine Dotmatics’ scientific intelligence with industrial AI technology and digital twins.” “This allows our customers to accelerate breakthroughs, reduce development cycles, and provide life-saving medicines to the market faster and more affordable.”
The transaction coincides with One Tech Company, the “one tech company” aimed at expanding the total addressable market for Siemens industrial software by $11 billion, accelerating innovation and creating value across the industry. Dotmatics is expected to generate more than $300 million in revenue in fiscal year 2025, with a adjusted EBITDA margin of over 40%, further strengthening Siemens’ growth profile. Dotmatics’ revenue growth and high profitability will be immediately taxed on Siemens growth, EBITDA margins and free cash flow before synergistic or special items. Siemens expects a substantial revenue synergy. The medium-term revenue synergy, which accelerates by approximately $100 million per year, will accelerate to more than $500 million per year in the long term.
About Siemens
Siemens AG (Berlin and Munich) is a leading technology company focused on industry, infrastructure, mobility and healthcare. The company’s purpose is to create technology that will change the way you live. By combining the real world and the digital world, Siemens will help customers accelerate digital and sustainability transformation, making factories more efficient, cities more liveable and transportation more sustainable. Siemens, a leader in industrial AI, leverages its deep domain know-how to include real-world applications including AI, which makes it accessible and impactful to customers across a wide range of industries.
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